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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLK1
All Species:
27.27
Human Site:
S492
Identified Species:
60
UniProt:
Q9UKI8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKI8
NP_036422.3
766
86700
S492
K
I
H
Q
L
N
K
S
W
R
D
E
K
K
E
Chimpanzee
Pan troglodytes
XP_001141231
787
89005
S513
K
I
H
Q
L
N
K
S
W
R
D
E
K
K
E
Rhesus Macaque
Macaca mulatta
XP_001084145
718
81923
S444
K
I
H
Q
L
N
K
S
W
R
D
E
K
K
E
Dog
Lupus familis
XP_535959
766
86670
S492
K
I
H
Q
L
N
K
S
W
R
D
E
K
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0V0
766
86605
S492
K
I
H
Q
L
N
K
S
W
R
D
E
K
K
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515053
718
81881
S444
K
I
H
Q
L
N
K
S
W
R
D
E
K
K
E
Chicken
Gallus gallus
XP_426581
764
86358
S490
K
I
H
Q
L
N
K
S
W
R
D
E
K
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90ZY6
756
85436
V478
F
E
Q
R
Y
A
A
V
K
I
H
Q
L
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624065
793
90042
D505
K
V
H
Q
L
N
K
D
W
K
E
D
K
K
A
Nematode Worm
Caenorhab. elegans
P34314
965
109255
D687
K
I
H
H
V
N
K
D
W
K
E
E
K
K
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39238
688
78131
L411
V
L
N
S
R
Y
A
L
L
N
L
L
G
K
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.5
99.4
N.A.
98.1
N.A.
N.A.
91.5
94.1
N.A.
83.2
N.A.
N.A.
46.4
37.9
N.A.
Protein Similarity:
100
97.3
93.7
99.7
N.A.
99.2
N.A.
N.A.
92.8
95.8
N.A.
89.4
N.A.
N.A.
61.2
50.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
N.A.
0
N.A.
N.A.
60
60
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
N.A.
20
N.A.
N.A.
86.6
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
19
0
0
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
19
0
0
64
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
19
73
0
0
64
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
82
10
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
73
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
82
0
0
0
0
0
82
0
10
19
0
0
82
91
10
% K
% Leu:
0
10
0
0
73
0
0
10
10
0
10
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
82
0
0
0
10
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
73
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
64
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _